鲁莉华,女,1979年11月生,博士,教授,硕士生导师
所属学科:化学工艺
研究方向:金属配合物在荧光检测中的应用
教育及工作经历:
2018.09–青岛农业大学化学工程与工艺教研室 教授
2013.12–2018.09 青岛农业大学物理化学教研室 副教授
2007.12–2013.12 bat365中文官网登录入口,物理化学教研室,讲师
2005.07-2007.10 青岛农业大学理学院,助教
2012.12–2015.12 香港浸会大学化学系,Dik-Lung Ma课题组攻读博士
2002.09–2005.07 青岛科技大学化工学院 化学工艺,硕士
1998.09–2002.07 青岛科技大学我院,精细化工,本科
科研与工作业绩:
主要从事铱(III)配合物的设计合成及其在生物荧光传感与药物研发上的应用研究工作。在农药残留检测、生物分析、有害物质检测以及基于铱(III)配合物药物研发领域取得了一些研究成果。主持国家自然科学基金青年项目、山东省自然科学基金面上项目、山东省高等学校科技计划项目和青岛市惠民计划项目各1项。在Chem. Sci., Anal. Chem., Chem. Commun., Biosens. Bioelectron., Acs Appl. Mater. Interfaces, Nanoscale等国际知名SCI期刊上发表研究论文50余篇。第一作者或通讯作者30余篇,影响因子6.0以上的22篇,H-index指数24。申请发明专利两项。
近五年代表成果列表:
- Y. Wang, F. Zhu, L. Yin, G. Qu, D.-L. Ma*, C.-H. Leung*, L. Lu*, Ratiometric fluorescent detection of pesticide based on split aptamer and magnetic separation. Sens. Actuat. B-Chem. 367 (2022) 132045 (Impact factor: 7.460, JCR一区)
- Y. Zhao, Y. Wang, R. Yang, H. Zhang, Y. Zhao, X. Miao*, L. Lu*,A zero-background fluorescent aptasensor for ultrasensitive detection of pesticides based on magnetic three-dimensional DNA walker and poly(T) -templated copper nanoparticles,Sens. Actuat. B-Chem., 343 (2021) 130172 (Impact factor: 7.460, JCR一区)
- X. Li, K. Fan, R. Yang, X. Du, B. Qu, X. Miao*, L. Lu*, A long lifetime ratiometrically luminescent tetracycline nanoprobe based on Ir(III) complex-doped and Eu3+-functionalized silicon nanoparticles, J. Hazard. Mater. 386 (2020) 121929. (Impact factor: 10.588, JCR一区)
- H. Su, M. Zang, L. Lu*, F. Li*, Monitoring matrix metalloproteases based on the selective interaction between an Ir(III) solvent complex and a histidine-rich polypeptide. Chem. Commun., 2019, 55, 7085-7088 (Impact factor: 6.164, JCR一区).
- L. Lu, H. Su, Q. Liu, F. Li*. Development of a Luminescent Dinuclear Ir(III) Complex for Ultrasensitive Determination of Pesticides. Anal. Chem. 2018, 90, 11716–11722. (Impact factor: 6.042, JCR一区)
- H. Zhang, M. Sun, Y. Wang, L. Yin, D.-L. Ma, C.-H. Leung, L. Lu*. A time-resolved ratiometric luminescent anthrax biomarker nanosensor based on an Ir(III) complex-doped coordination polymer network. J. Mater. Chem. B, 10 (2022), 1853-1857. (Impact factor: 6.331, JCR一区)
- Y. Wang , G. Qu, L.Yin, Q. Liu, R. Yang, L. Lu*, Ratiometric detection of transcription factor based on Europium(III) complex-doped silicon nanoparticles and a G-quadruplex-selective Iridium(III) complex. Anal. Chim. Acta 1209 (2022) 339855. (Impact factor: 6.558, JCR一区)
- X. Tang, K. Fan, B. Qu, L. Lu*, A luminescent microRNA nanoprobe based on the target-triggered release of an iridium(III)-solvent complex from mesoporous silica nanoparticles. Microchim Acta, 2019, 186, 841. (Impact factor: 5.479, JCR二区)
- X. Li, K. Fan, W. Kang, R. Yang, B. Qu, L. Lu*,γ-Aminobutyric acid-modified graphene oxide as a highly selective and low-toxic fluorescent nanoprobe for relay recognition of copper(II) and cysteine. Microchim Acta, 2019, 186, 461-469 (Impact factor: 5.479, JCR二区)
- K. Fan, W. Kang, S. Qu, L. Li, B. Qu, L. Lu*, A label-free and enzyme-free fluorescent aptasensor for sensitive detection of acetamiprid based on AT-rich dsDNA-templated copper nanoparticles. Talanta, 2019, 197, 645-652. (Impact factor: 4.916, JCR二区)
近五年主持科研项目:
(1)国家自然科学基金青年项目,新型双核发光铱(Ⅲ)配合物的设计、合成及其在转录因子检测中的应用研究,21705089,2018.01–2020.12,主持
(2)山东省自然科学基金面上项目,功能性双核发光铱(Ⅲ)配合物的设计、合成及其在肿瘤标志物检测中的应用研究,ZR2017MB064,2017.08–2020.06, 主持
(3)青岛市科技计划项目,动力学惰性铱(Ⅲ) 配合物的设计、合成及其在Aβ肽纤维化中的应用研究,18-6-1-83-nsh,2018.09–2020.09,主持
(4)山东省高等学校科技计划项目,基于新型双核发光铱(Ⅲ)配合物的肿瘤标志传感新方法研究,J17KA109,2017.05-2019.12,主持
联系方式:
电话:13954297004
邮箱: lulihua2012@qau.edu.cn